ABSTRACT
The route of transmission of Novel SARS-CoV-2 virus is ambiguous. In this regard we planned a study to find out SARS-CoV-RNA shedding in various clinical samples of 9 COVID-19 positive patients. SARS-CoV-RNA was detected in nasal swab (NS), throat swab (TS) and faecal sample but was not detected in serum and urine samples. We also report that SARS-CoV-2-RNA persisted in faeces for >20 days. Persistence of faecal RNA might impose challenge in infection control and the disease may spread to household contacts if discharged. Perineal cleaning and hygiene may be advised at the time of vaginal delivery.
Subject(s)
COVID-19/epidemiology , COVID-19/virology , RNA, Viral , SARS-CoV-2 , Adolescent , Adult , COVID-19/diagnosis , Child , Child, Preschool , Feces/virology , Female , Humans , Male , Middle Aged , Nasal Cavity/virology , Pharynx/virology , Time Factors , Viral Load , Young AdultSubject(s)
Amides/therapeutic use , Antiviral Agents/therapeutic use , Coronavirus Infections/drug therapy , Pneumonia, Viral/drug therapy , Pyrazines/therapeutic use , Virus Shedding/drug effects , Administration, Oral , Aged , Amides/administration & dosage , Antiviral Agents/administration & dosage , Betacoronavirus , COVID-19 , Female , Humans , Male , Middle Aged , Pandemics , Pyrazines/administration & dosage , RNA, Viral/analysis , SARS-CoV-2ABSTRACT
In a family experiencing coronavirus disease 2019, the parents and 2 children aged 2 and 5 years became infected but the youngest child was not infected. Both children initially shed infectious virus, but cleared the virus after 5 to 6 days in the nasopharynx. However, viral RNA was continuously detected in the children's stool for more than 4 weeks.